ethyl 2,2-difluoro-3-oxobutanoate

ethyl 2,2-difluoro-3-oxobutanoate - Names and Identifiers

Name	Ethyl 2,2-difluoroacetoacetate
Synonyms	Ethyl 2,2-difluoroacetoacetate ETHYL 2,2-DIFLUOROACETOACETATE Ethyl 2,2-difluoro-3-oxobutanoate ethyl 2,2-difluoro-3-oxobutanoate 2,2-difluoro-acetoaceticacidethylester 2,2-Difluoroacetoacetic acid ethyl ester 2,2-DIFLUORO-3-OXO-BUTYRIC ACID ETHYL ESTER Butanoic acid, 2,2-difluoro-3-oxo-, ethyl ester
CAS	2266-48-0
EINECS	000-000-0
InChI	InChI=1/C6H8F2O3/c1-3-11-5(10)6(7,8)4(2)9/h3H2,1-2H3

ethyl 2,2-difluoro-3-oxobutanoate - Physico-chemical Properties

Molecular Formula	C6H8F2O3
Molar Mass	166.12
Density	1.2726 g/cm3(Temp: 0 °C)
Boling Point	162°C
Flash Point	162°C
Vapor Presure	2.3mmHg at 25°C
BRN	1769592
Storage Condition	2-8°C
Refractive Index	1.4070
MDL	MFCD00190633

ethyl 2,2-difluoro-3-oxobutanoate - Risk and Safety

Risk Codes	R10 - Flammable R36/38 - Irritating to eyes and skin.
Safety Description	S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	1993
Hazard Class	3
Packing Group	III

ethyl 2,2-difluoro-3-oxobutanoate - Introduction

Ethyl 2,2-difluoroacetoacetate, also known as Ethyl 2,2-difluoroacetoacetate, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: colorless liquid
-Molecular formula: C6H7F2O3
-Molecular weight: 168.11g/mol
-Melting point:-56 ° C
-Boiling point: 108-110 ° C
-Density: 1.314g/cm3
-Soluble: Soluble in ethanol, ether and chlorinated hydrocarbons

Use:
- Ethyl 2,2-difluoroacetoacetate can be used as an important intermediate in organic synthesis, for the synthesis of drugs, pesticides and dyes and other compounds.
-It can also be used to prepare fluorinated compounds, halogenated ketones and other fluorine-containing compounds.

Method:
- Ethyl 2,2-difluoroacetoacetate is usually synthesized by the following steps:
1. Ethyl acetoacetate is reacted with difluoromethanyl chloride to generate chloroethyl 2,2-difluoroacetoacetate.
2. React chloroethyl 2,2-difluoroacetoacetate with ethanol to generate Ethyl 2,2-difluoroacetoacetate under the catalysis of alkali.

Safety Information:
- Ethyl 2,2-difluoroacetoacetate is irritating and should be avoided in contact with skin, eyes and mucous membranes.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during use or handling.
-Avoid fire and high temperature during storage and use to prevent it from burning and exploding.
-Waste disposal should comply with local laws and regulations to avoid environmental impact.

Last Update：2024-04-09 02:00:44